Layer-by-layer deposition of oppositely charged polyelectrolytes on the surface of condensed DNA particles
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چکیده
منابع مشابه
Layer-by-layer deposition of oppositely charged polyelectrolytes on the surface of condensed DNA particles.
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding the core of condensed DNA. Using poly-L-lysine (PLL) and succinylated PLL (SPLL) as polycation and polyanion, respectively, we demon...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1999
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/27.15.3090